WEBVTT 00:00:00.000 --> 00:00:00.500 align:middle line:90% 00:00:00.500 --> 00:00:02.550 align:middle line:84% As you know, cancer is a very broad word 00:00:02.550 --> 00:00:06.150 align:middle line:84% and could encompass relatively minor cancer 00:00:06.150 --> 00:00:08.550 align:middle line:84% with perhaps no implications or no difference 00:00:08.550 --> 00:00:11.610 align:middle line:84% from someone who is otherwise healthy, with regards 00:00:11.610 --> 00:00:14.580 align:middle line:84% to COVID-19, to a more extreme situation where 00:00:14.580 --> 00:00:18.150 align:middle line:84% a patient with cancer might be facing a situation of more 00:00:18.150 --> 00:00:20.400 align:middle line:84% advanced disease, or a treatment that might 00:00:20.400 --> 00:00:22.180 align:middle line:90% be more immunosuppressive. 00:00:22.180 --> 00:00:24.928 align:middle line:84% That is that would bring the immune system down more 00:00:24.928 --> 00:00:25.470 align:middle line:90% than average. 00:00:25.470 --> 00:00:28.060 align:middle line:84% And then, particularly in those groups of patients, 00:00:28.060 --> 00:00:31.843 align:middle line:84% we might think of a different way to approach their care. 00:00:31.843 --> 00:00:34.260 align:middle line:84% So we're getting a large number of questions at this point 00:00:34.260 --> 00:00:38.130 align:middle line:84% from patients who understandably are concerned and want 00:00:38.130 --> 00:00:40.590 align:middle line:84% to understand better what a potential infection 00:00:40.590 --> 00:00:42.750 align:middle line:90% with COVID-19 might mean. 00:00:42.750 --> 00:00:45.270 align:middle line:84% From what we know, infection with COVID-19 00:00:45.270 --> 00:00:49.110 align:middle line:84% seems to be more difficult, more aggressive, and with worse 00:00:49.110 --> 00:00:51.660 align:middle line:84% outcomes in people who are, in general, unwell 00:00:51.660 --> 00:00:53.560 align:middle line:90% and of advancing age. 00:00:53.560 --> 00:00:56.610 align:middle line:84% And what we're seeing is this is predominantly in older males 00:00:56.610 --> 00:00:59.060 align:middle line:90% that we have seen the effect. 00:00:59.060 --> 00:01:01.520 align:middle line:84% We don't yet understand all the comorbidities, 00:01:01.520 --> 00:01:03.440 align:middle line:84% but what we're telling patients as we're 00:01:03.440 --> 00:01:06.380 align:middle line:84% getting this questions, that until we know more 00:01:06.380 --> 00:01:10.820 align:middle line:84% it is prudent for them to be extra cautious, and hopefully 00:01:10.820 --> 00:01:13.820 align:middle line:84% through those behaviors prevent them becoming 00:01:13.820 --> 00:01:15.560 align:middle line:90% infected with COVID 19. 00:01:15.560 --> 00:01:18.230 align:middle line:84% So be extra careful with regards to the sanitation 00:01:18.230 --> 00:01:21.350 align:middle line:84% of your hands, the good practice of social distancing 00:01:21.350 --> 00:01:23.390 align:middle line:84% that we have all seen in the news, 00:01:23.390 --> 00:01:25.730 align:middle line:84% and certainly try to avoid exposure to individuals 00:01:25.730 --> 00:01:28.430 align:middle line:90% who may be potentially ill. 00:01:28.430 --> 00:01:30.590 align:middle line:84% Furthermore, some treatments may affect different 00:01:30.590 --> 00:01:34.737 align:middle line:84% how a person may be able to fight off an infection or not. 00:01:34.737 --> 00:01:36.320 align:middle line:84% Some of the treatments that bring down 00:01:36.320 --> 00:01:39.350 align:middle line:84% a certain type of white cells create 00:01:39.350 --> 00:01:40.760 align:middle line:90% what we call myelosuppression. 00:01:40.760 --> 00:01:43.280 align:middle line:84% That is that the neutrophils are down. 00:01:43.280 --> 00:01:44.930 align:middle line:84% That is usually thought of to be more 00:01:44.930 --> 00:01:47.540 align:middle line:84% important for bacterial infections. 00:01:47.540 --> 00:01:50.750 align:middle line:84% Some other cancer treatments may affect more the way 00:01:50.750 --> 00:01:52.100 align:middle line:90% our immune system responds. 00:01:52.100 --> 00:01:54.620 align:middle line:84% And there's a number of cells there, like the lymphocytes, 00:01:54.620 --> 00:01:57.120 align:middle line:84% so maybe that's more important for viruses. 00:01:57.120 --> 00:01:59.150 align:middle line:84% But this is all speculative, because we really 00:01:59.150 --> 00:02:01.930 align:middle line:84% don't have the information at this point. 00:02:01.930 --> 00:02:05.000 align:middle line:90%